I estimate a registry cleaner would, indeed, solve a runtime error 90 to 95% of the time.  However, be aware of the great deceiver, malware.  Since malware invades registries it can cause the registry to corrupt in such a way it would be prone to runtime errors.  In this case, a regisatry cleaner would cure the registry problem but in a short time the malware would corrupt the registry again causing the runtime error to raise its ugly head once more.

To be sure you fix this error, make sure your virus cleaner is capable of areesting all malware. Most virus cleaners are not.  So, you may have to run  a top notch spyware cleaner such as antispyware plus.  Then after you are sure you are malware free, run the registry cleaner.

photo credit: valentin.d

Post from theWindows Registry Cleaner blog where you get up to date registry cleaning, scanning and optimization information.

Runtime Error r6025

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4. Windows Vista Registry Checker